The molar solubility of sodium acetate was measured in binary mixtures of methanol, 1-propanol, acetonitrile, and water along with the density of their saturated solutions at 298.2 K. The molar solubilities span a range of nearly 4 orders of magnitude from 5.53 mol.L-1 in water to 0.0014 mol.L-1 in acetonitrile, the according values for the mole fraction solubilities are 0.119 and 0.00007. For the calculation of the solubility and the density at any composition of the binary solvent mixture, a computational method is provided, based on the Jouyban-Acree model. The method uses the solubility data in the monosolvents and their density and model constants; the latter are derived by fitting the experimental data to the Jouyban-Acree model. Solubilities and densities were back-calculated, and the overall mean percentage deviations between experimental and calculated values were 9.8 % for the solubilities and 0.4 % for the densities of the saturated solutions.