Solubility data of furan-2-carboxylic acid in six pure solvents and two kinds of binary solvent mixtures were measured from 279.35 K to 326.15 K. The effect of solvent and temperature on the solubility of furan-2-carboxylic acid was discussed. The experimental solubility data of furan-2-carboxylic acid in six pure solvents were correlated by four thermodynamic models. The nearly ideal binary solvent (NIBS)/Redlich-Kister model was used to correlate the solubility data in binary solvent mixtures. In addition, the melting temperature and fusion enthalpy of furan-2-carboxylic acid were measured by differential scanning calorimetry. By using solubility data and the van't Hoff equation, the dissolution entropy, enthalpy, and molar Gibbs free energy of fiiran-2-carboxylic acid in pure solvents were also obtained and analyzed.