Excess molar enthalpies for the binary and ternary mixtures of (cyclohexane, 1,4-dioxane, and piperidine) and (cyclohexane, morpholine, and piperidine) were measured using a Calvet microcalorimeter at 308.15 K and atmospheric pressure. The empirical equations of Redlich-Kister and Cibulka were used to correlate the experimental excess molar enthalpies for the binary and ternary mixtures, respectively. The capability of artificial neural network algorithm to model these data is also studied.