In this paper we investigated the fatigue damage of a unidirectional flax-reinforced epoxy composite using infrared (IR) thermography. Two configurations of flax/epoxy composites layup were studied namely, [0](16) unidirectional ply orientation and [+/- 45](16). The high cycle fatigue strength was determined using a thermographic criterion developed in a previous study. The fatigue limit obtained by the thermographic criterion was confirmed by the results obtained through conventional experimental methods (i.e., Stress level versus Number of cycles to failure). Furthermore, a model for predicting the fatigue life using the IR thermography was evaluated. The model was found to have a good predictive value for the fatigue life. In order to investigate the mechanism of damage initiation in flax/epoxy composites and the damage evolution, during each fatigue test we monitored the crack propagation for a stress level and at different damage stages, a direct correlation between the percentage of cracks and the mean strain was observed.