The UV/H2O2 advanced oxidation process is increasingly applied as a barrier against organic micro pollutants in drinking water treatment. Adequate modeling of the purification process, resulting in a reliable prediction of the reactor performance, would make it possible to optimize the operating parameters as a function of seasonal or diurnal fluctuations in the influent composition, and thus save energy while still guaranteeing safe drinking water. We recently developed two design tools to predict full scale performance of UV/H2O2 reactors: the UVPerox land II models. UVPerox I is based on a kinetic model, describing both photolysis and oxidation. By means of Computational Fluid Dynamics (CFD) calculations of the reactor the UV dose distribution inside the reactor can be calculated, while the kinetic model gives the conversion as a function of the UV dose. UVPerox I is shown to be applicable to reactors equipped with Low Pressure (LP) or Dielectric Barrier Discharge (DBD) UV lamps, using a broad range of organic compounds, resulting in a <5-10% deviation from experimental data for different water matrix compositions. The conversion of micro pollutants as a function of the UV dose can also be experimentally determined, using a collimated beam (CB) set-up. The dose response curves thus obtained can also be directly implemented in the CFD-model of the reactor (UVPerox II). Using several model compounds UVPerox II is shown to be applicable to reactors equipped with three kinds of UV lamps (LP-, MP- UV and DBD lamps), each with its own emission spectrum. The deviation from experimental data was found to be <5-10%, independent of the composition of the water matrix. Both models were applied to several reactor geometries. Good agreement was obtained between both models and the actual conversion data for three types of UV lamps in various pilot reactors and water types. (C) 2012 Elsevier B.V. All rights reserved.