Pellet coating is commonly performed in a fluid bed coater such as a Wurster coater. Computational fluid dynamics (CFD) simulations and experimental measurements of laboratory-scale Wurster coating were performed. CFD simulations were performed in a 2D axisymmetric space using the two-fluid model. The effect of the Wurster gap and fluidizing airflow rate on gas-solid flow was analyzed in both simulations and experiments. Experimentally, the draft tube two-phase flow was evaluated by measuring the volume fraction of pellets within the draft tube and local particle velocities at the tube exit and by monitoring the local pressure drop fluctuations. A rather good agreement between the simulated and experimental results was observed and thus it can be assumed that this particular simulation setup represents a computationally reasonable tool that provides a valuable insight into the Wurster coating process due to the impact of two-phase flow properties on the process. (C) 2013 Elsevier Ltd. All rights reserved.