Computer-aided multiscale modelling (CAMM) may be carried out in three consecutive stages, namely conceptual modelling, model realization, and model execution. Following earlier work on a conceptual modelling tool which aims to support the first stage of CAMM, prototypical tools for realizing conceptual models and for the execution of simulation are developed in this work, with the assumption that a multiscale simulation is to be carried out by means of integrating existing single-scale models. More specifically, the tool that supports model realisation helps modellers generate information required for executing the multiscale model. The model execution stage is in turn supported by a component-based simulation environment. Two different multiscale simulation modes, namely "coordinator driven" and "master tool driven", are identified and supported separately. Details of the design and implementation of these tools are provided. Two reactor modelling examples are used to validate these tools and to demonstrate their application. (C) 2012 Elsevier Ltd. All rights reserved.