The effect of vanadium incorporation on the HDS, HDN, and HDA activities of LCO hydrotreating was investigated on NiMo supported hydrotreating catalysts. The catalysts were characterized by XRD, BET, XPS, NO-chemisorption and evaluated in fixed bed reactor using real LCO as feed. The vanadium promoted NiMo catalyst presented higher HDS and HDN activities, and surprisingly a relatively low activity toward the HDA. This behavior is probably due to a vanadium-mixed active phase, this has superior conversion as compared to NiMo catalyst (c) 2013 Elsevier B.V. All rights reserved.