Flow condensation heat transfer coefficients (HTCs) and pressure drop of R22, propylene, propane, DME and isobutane are measured on a horizontal plain tube. The main test section in the experimental flow loop is made of a plain copper tube of 8.8 mm inner diameter and 530 mm length. The refrigerant is cooled by passing cold water through the annulus surrounding the test section. Tests are performed at a fixed refrigerant saturation temperature of 40 +/- 0.2 degrees C with mass fluxes of 100, 200, and 300 kg/m(2) s and heat flux of 7.3-7.7 kW/m(2). The heat transfer and pressure drop data are obtained in the vapor quality range of 10-90%. Test results show that for a given mass flux the flow condensation HTCs of propylene, propane, DME and isobutane are higher than those of R22 by tip to 46.8%, 53.3%, 93.5% and 61.6%, respectively. Also well-known correlations developed based upon conventional fluorocarbon refrigerants predict the present data within a mean deviation of 33%. Finally, the pressure drop increases as the mass flux and quality increase and isobutane shows the highest pressure drop due to its lowest vapor pressure among the fluids tested. (c) 2008 Elsevier Ltd. All rights reserved.