Blends of poly(ethylene 2,6-naphthalate)(PEN) and poly(butylene terephthalate) (PBT) were prepared by both solution and melt methods. Any significant difference was not observed for the glass transition and melting temperatures. These blends showed a partial compatibility based on the glass transition temperatures. PEN and PBT crystallized separately to exhibit two melting temperatures. The crystallization rate of PEN in PEN-rich blends was not affected by the PVT content, while that of PVT in PVT-rich blends decreased with an increase of the PEN content. By comparing the experimental modulus and strength with those predicted from Kleiner's and Paul's model, PEN/PBT blends can be described to have some compatibility throughout the compositions.