New mechanistic bubble coalescence and break-up models considering turbulent suppression phenomena, which can possibly occur in the high liquid velocity condition of turbulent bubbly two-phase flow, are presented. The energy exchange mechanism between a turbulent eddy and interfacial structure was taken into account in the efficiency terms. Numerical simulations of turbulent bubbly flow were conducted in a CFD code to evaluate the newly developed models, in comparison with other advanced models coupled with a bubble-induced turbulent effect for one-group interfacial area transport equation. Local measurements of the bubble characteristics on the bubble size evolution along a vertical pipe flow were performed at KAERI-VAWL test facility using the five-sensor conductivity probe method to provide database for models validation. Results from the calculation clearly show the improvements of the newly developed models. (C) 2013 Elsevier Ltd. All rights reserved.