We used a heating surface composed of a hydrophilic substrate with hydrophobic dots to characterize the effect of spatially-different surface characteristics on critical heat flux (CHF) and nucleate boiling. To ascertain important surface factors that control CHF and boiling on heterogeneous wetting surfaces, we adjusted the hydrophobic dot diameter and the relative pitch between adjacent dots. Based on the dynamics of bubbles on hydrophobic dots, we analyze the trend of CHF on differently-fabricated heterogeneous wetting surfaces. CHFs on heterogeneous wetting surfaces were strongly dependent on ratio R of the area covered by hydrophobic dots to the heated area, but independent on the diameter of hydrophobic dots and the pitch distance. The improvement of boiling heat transfer (BHT) varied according to the conditions, and appeared to be related to the diameter, pitch distance and the number of hydrophobic dots, but the effect of R on BHT was negligible. Based on this study, we propose optimized conditions of a hydrophobic patterned surface. To sustain high CHF of a hydrophilic surface and high BHT of a hydrophobic surface, numerous micron-size hydrophobic dots should be fabricated with small R. (C) 2014 Elsevier Ltd. All rights reserved.