In the present investigation, Poly [(4-aminophenyl)sulfonyl]butanediamide (PASB) and methylated Poly[(4-aminophenyl)sulfonyl] butanediamide (mPASB) polymers were synthesized, using succinyl chloride and substituted 4-amino-1-benzenesulphonamide. Polysulfone composite membranes were prepared by blending these novel polymers by Diffusion Induced Phase Separation (DIPS) method. The performance of the membrane was studied in terms of salt rejection, water flux and molecular weight cutoff. The prepared membranes were hydrophilic in nature, which was confirmed by water uptake studies and contact angle measurement. All the membranes showed 1000 Da molecular weight cutoff. A maximum NaCl rejection of 52% was observed in some of the membranes. The effect of feed NaCl concentration on the NaCl rejection was also studied. The resistance of the membranes in a wide pH range was studied by water uptake measurement. Antifouling properties of the membranes were also performed using Bovine Serum Albumin (BSA) solution. (C) 2012 Elsevier B.V. All rights reserved.