Quantum chemistry methods have been applied to study the influence of the Xe atom inserted into the hydrogen bromine bond (HBr -> HXeBr), particularly on the nature of atomic interactions in the HBr center dot center dot center dot CO2 and HXeBr center dot center dot center dot CO2 complexes. Detailed analysis of the nature of chemical bonds has been carried out using topological analysis of the electron localization function, while topological analysis of electron density was used to gain insight into the nature of weak nonbonding interactions. Symmetry-adapted perturbation theory within the orbital approach was applied for greater understanding of the physical contributions to the total interaction energy.