4-Amino-3-thio-1,2,4-triazolidine (L(I)) and 4-amino-5-thio- 1,3,4-thiadiazole (L(II)) as well as their metal complexes of the general formulae ML(I).2H(2)O and ML(II)Cl (M; Pb(II), Cd(II) and Zn(II) were prepared. With Sn(II), we obtained Sn(L(I))(2).2H(2)O and SnL(II)Cl, respectively. The structures of the compounds were identified through elemental analysis, and IR and UV spectra measurements, in addition to thermal analysis in case of the metal complexes. The antifouling properties of the compounds were tested by their incorporation into paint formulations which were applied to PVC substrates and tested in water from Alexandria western harbour. When the compounds were added at 17.5% by volume, the coated panels were fouled after 3 months of immersion. The addition of 6.7% by volume of tributyltin oxide to 15.8% of the prepared compounds in one formulation elevated the paint efficiency and prevented fouling for 11 months. Paint containing solely tributyltin oxide at the same concentration was inactive against algae.