Magnetic field effect on the phase transition at high temperature (from 50 degrees C) inside the magnetic field has been found in C(14)G(2) (N-tetradecyllactobionamide)/C12EO4 (tetraethylene glycol monododecyl ether)/D2O system. The phase was transited quickly from lamellar phase to isotropic phases [bottom, micellar phase (L-1 phase) and top, sponge phase (L-3 phase)] induced by a magnetic field, which was demonstrated by H-2 NMR and FF-TEM measurements. The isotropic phases induced by magnetic field were not stable, and the upper L3 phase can recover to lamellar phase after being restored in a 55 degrees C thermostat outside the magnetic field for about one month. During the mechanism study, the C12EO4 molecule was proved to be the dominant component for the phase transition induced by the magnetic field, while the C(14)G(2) molecule was the auxiliary and just affected the transition speed. The breaking and rebuilding of hydrogen bonds could play an important role in the phase transition and recovering. Moreover, the surfactant concentration had an effect on the speed of phase transiting and phase recovering. These observations could provide an understanding. of the phase transition and also the applications for the controlled drug delivery system of bilayer membranes driving, induced by the magnetic field.