The series of polycrystalline ferrite samples were investigated to fix the specific electromagnetic and structural parameters which lead to the generation of domain-acoustics echo (DAE). It was found that DAE occurs only in materials with a high symmetry of a crystalline structure (spinels and garnets). The maximum DAE response may be attained in manganese-containing ferrites The coercitivity must exceed 0.1 kA/m and saturation magnetization be more than 130 and 400 kA/m for garnet and spinel accordingly. The strong correlation of the DAE signal characteristics with the value of the crystal grain size D-a and degree of a structural homogeneity of the polycrystalline ferrites was determined. For the garnet samples the DA-E signal increases with the grain size decreasing (D-a less than or equal to 10 mkm). In all cases the porosity must be less of 1.5-2%. Precise thin boundaries of the crystallite are required.