Wollastonite and dicalcium. silicate coatings have been prepared on Ti-6Al-4V substrate via plasma spraying. Bond strength test, simulated body fluid (SBF) immersion, in vitro cell culturing, and in vivo implantation were carried out to evaluate their mechanical and biological characteristics. The results obtained showed that both coatings possess higher bond strength as compared with hydroxyapatite (HA) coating. In the meanwhile, the good bioactivity and biocompatibility were confirmed in this study.