In this paper TEM work on the formation of dislocation meshes, cells, microbands and shear bands is summarized. Following this the results of a sequential rolling experiment in which the development of microstructure is followed from the strain free to 50% rolling condition. Crystals behave according to three generic types. Grains with an orientation close to alpha, deform homogenously without much rotation. Grains close to {111}< 110 > are also stable, and can have either alpha or gamma microstructure. Others seem to be able to deform homogenously up to a certain strain, hence resembling a grains, and then rotate to gamma, forming typical gamma microstructures.