This paper contains a review of microstructural through-process modelling (TPM) and the particular role of ingot metallurgy from an industrial perspective, focusing on recent advances in solidification theory, solidification and homogenisation software, and software environments that allow models to interface. To illustrate how as-cast microstructure can impact on downstream processing steps, a sensitivity analysis has been performed on an AA1xxx alloy using an in-house homogenisation model. Thus, knowledge gaps in theory and model application are highlighted.