A Facile Preparation of 2,2'-Diphenyl-4,4'-dihydroxybiphenyl - A New Synthetic Route

Jin-Young Bae

Journal of Industrial and Engineering Chemistry, Vol.4, No.4, 319-323, December, 1998

Export Citation

A Facile Preparation of 2,2'-Diphenyl-4,4'-dihydroxybiphenyl - A New Synthetic Route

Jin-Young Bae^†

Department of Polymer Science and Engineering, Sung Kyun University, Suwon 440-746, Korea

E-mail:

Nickel(0)-catalyzed homocoupling of aryl mesylate of 4-protected-2-substituted hydroquinone was utilized in the key step of a reaction scheme which leads to the synthesis of 2,2'-diphenyl-4,4'-dihydroxybiphenyl. The new synthetic procedure reported in this paper started from the commercially available 2-phenylphenol as a starting material.

Keywords:transition metal;nickel catalyst;homocoupling;Fries rearrangement;2;2'-diphenyl-4;4'-dihydroxy-biphenyl

[References]

Percec V, Bae JY, Zhao M, Hill DH, J. Org. Chem., 60, 176 (1995)
Percec V, Bae JY, Zhao M, Hill DH, J. Org. Chem., 60, 1066 (1995)
Venanzi LM, J. Chem. Soc., 719 (1958)
Auwers KV, Wittig G, J. Prakt. Chem., 108, 99 (1924)
Borsotti G, Foa M, Eur. Patent, 0337434A2 (1989)
Crossland RK, Servis KL, J. Org. Chem., 35, 3195 (1970)
Bae JY, Percec V, J. Ind. Eng. Chem., 4(1), 64 (1998)

[Related Articles]

[1] Percec V, Bae JY, Zhao M, Hill DH, J. Org. Chem., 60, 176 (1995)

[2] Percec V, Bae JY, Zhao M, Hill DH, J. Org. Chem., 60, 1066 (1995)

[3] Venanzi LM, J. Chem. Soc., 719 (1958)

[4] Auwers KV, Wittig G, J. Prakt. Chem., 108, 99 (1924)

[5] Borsotti G, Foa M, Eur. Patent, 0337434A2 (1989)

[6] Crossland RK, Servis KL, J. Org. Chem., 35, 3195 (1970)

[7] Bae JY, Percec V, J. Ind. Eng. Chem., 4(1), 64 (1998)