Tetrasodium ethylenediaminetetraacetate (Na(4)EDTA) is a chelating agent extensively used in a variety of industrial sectors to complex metal ions. For this reason, its presence in wastewaters and therefore in the aquatic environment is a matter of interest. In this work, a 5000 Da multichannel ceramic membrane was used in order to remove Na(4)EDTA from model aqueous solutions at concentrations between 0.07% and 5.0%w/w. Na(4)EDTA present in the permeate and retentate streams was quantified by high performance liquid chromatography using ultraviolet detection of the FeNaEDTA complex formed in the previous sample derivatization steps. The results showed that Na(4)EDTA rejection strongly depends on the feed concentration due to the screening effect of membrane charge. The Spiegler-Kedem model was applied to study the mass transfer of solutes through the membrane. Its application was found to be limited to low and intermediate permeate fluxes, since a deviation was appreciated at higher fluxes in all experiment runs. (C) 2013 Elsevier B.V. All rights reserved.