In this article, a transient simulation model and the EnergyPlus were used to study the energy performance and economical feasibility for integrating a solar liquid desiccant dehumidification system with a conventional vapor compression air-conditioning system for the weather condition of Hong Kong The vapor compression system capacity in the solar assisted air-conditioning system can be reduced to 19 kW from original 28 kW of a conventional air conditioning system as a case study due to the solar desiccant cooling The economical performance of the solar desiccant dehumidification system is compared with that of the conventional air-conditioning system The results show that the energy saving potentials due to incorporation of the solar desiccant dehumidification system in a traditional air-conditioning system is significant for the hot wet weather in Hong Kong due to higher COP resulted from higher supply chilled water temperature from chiller plants The annual operation energy savings for the hybrid system is 6760 kWh and the payback period of the hybrid system is around 7 years The study shows that the solar assisted air-conditioning is a viable technology for utilizations in subtropical areas (C) 2010 Elsevier Ltd All rights reserved