The sedimentation of aqueous silica suspensions has been studied by means of time domain dielectric spectroscopy (TDDS) in the frequency range 20 MHz to 2 GHz. The experiments were designed with a 2(5-1) reduced factorial design and analyzed in terms of multivariate regression models. Five different variables were varied to investigate the corresponding suspension sedimentation. The influence of the different variables on the sedimentation of the silica suspensions is discussed.