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Thermochimica Acta, Vol.580, 1-6, 2014
DSC study and calculation of metronidazole and clarithromycin thermodynamic melting parameters for individual substances and for eutectic mixture
In this study melting thermodynamic characteristics of clarithromycin and metronidazole as individual substances were investigated by DSC method. It was found that the binary system of clarithromycin and metronidazole is a system with simple eutectic. Composition, melting temperature and the heat of fusion of the eutectic were determined by calculation and experimental methods. (C) 2014 Elsevier B.V. All rights reserved.