화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korean Journal of Materials Research, Vol.15, No.5, 353-360, May, 2005
DOI10.3740/MRSK.2005.15.5.353  Export Citation
H 2 O 2 /HCl 처리한 Ti 임플란트의 생체활성 평가
aluation of Bioactivity of Titanium Implant Treated with H 2 O 2 /HCl Solution
유재선, 권오성, 이오연, 이민호1, †, 송기호2
  • 전북대학교 신소재공학부
  • 1전북대학교 치과생체재료학교실 및 구강생체과학연구소
  • 2전주공업대학 자동차과
J.S. Yue, O.S. Kwon, O.Y. Lee, M.H. Lee1, †, and K.H. Song2
  • School of Advanced Materials Engineering, Chonbouk National University, Chonju, 561-756, Korea
  • 1Dept. of Dental Biomaterials and Institute of Oral Bioscience, Chonbouk National University, Chonju, 561-756, Korea
  • 2Dept. of Automobile, Jeonju Technical College, Chonju 560-760, Korea
E-mail:
Surface treatment play an important role in nucleating calcium phosphate deposition on surgical Ti implant. Therefore, the purpose of this study is to examine whether the precipitation of apatite on cp-Ti and Ti alloys are affected by surface modification in HCl and H 2 O 2 solution. Specimens were then chemically treated with a solution containing 0.1 M HCl and 8.8M H 2 O 2 at 80 ? C for 30 mins, and subsequently heat-treated at 400 ? C for 1 hour. All specimens were immersed in the HBSS with pH 7.4 at 36.5 ? C for 15 days, and the surface was examined with XRD, SEM, EDX ana XPS. Also, pure Ti, Ti-6Al-4V and Ti-6Al-7Nb alloy specimens with and without surface treatment were implanted in the abdominal connective tissue of mice for 4 weeks. All specimens chemically treated with HCl and H 2 O 2 solution have the ability to form a apatite layer in the HBSS which has inorganic ion composition similar to human blood plasma. The average thickness of the fibrous capsule surrounding the specimens implanted in the connective tissue was 38.57μm,62.27μmand45.64μm in the cp-Ti, Ti-6Al-4V ana Ti-6Al-7Nb alloy specimens with the chemical treatment respectively, and 52.20μm,75.62μmand66.56μm in the commercial specimens of cp-Ti, Ti-6Al-4V and Ti-6Al-7Nb without any treatment respectively. The results of this evaluation indicate that the chemically treated cp-Ti, Ti-6Al-4V ana Ti-6Al-7Nb alloys have better bioactivity and biocompatibility compared to the other metals tested.
Keywords:chemical surface treatment;biocompatibility;bioactivity;mouse abdominal connective tissue
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