Fe-doped mesoporous metal oxides (Fe/MO2, M = Si and Ti) were synthesized with particle size in the range of 10-15 nm via modified sal-gel method. The Fe modified SiO2 and TiO2 have proved to be very efficient catalysts in three-component coupling of aldehydes, alkynes and amines for the solvent-free synthesis of proargylamines. Among the two Fe-doped metal oxide catalysts, Fe/TiO2 gives 94% propargylamine yield at 245W microwave power for few minutes under solvent free condition and found to be a better catalyst. With a Fe/TiO2 heterogeneous catalyst and in the absence of solvent, the proposed process for propargylamine synthesis is green and environmentally benign protocol. (C) 2014 Elsevier B.V. All rights reserved.