In recognition of the growing demand regarding the control of undesired taste and odor (T&O) problems in natural water resources, the photocatalytic degradation of 2-isopropyl-3 methoxy pyrazine (IPMP), a common metabolite of soil actinomycetes which contributes a rotten vegetable odor to water, was investigated under simulated solar irradiation. Under the studied conditions (C = 10 mg L-1, C-TiO2 = 100 mg L-1 and I = 600 W m(-2)), 95% of IPMP was removed within 20 min of irradiation. The reaction intermediates were completely mineralized to CO2 and the nitrogen was predominantly released as NH4+ ions after 240 min irradiation. The major transformation products of TiO2 photocatalysis of IPMP have been determined by the use of high resolution accurate liquid chromatography-orbitrap mass spectrometry as well as gas chromatography-mass spectrometry (GC-MS) techniques. Hydroxylation of the isopropyl and methoxy groups has been identified as the main reaction pathway. Scavenging experiments indicated the important role of HO center dot, h(+) and O-2(center dot-) in the photocatalytic process. Toxicity assessment revealed the efficiency of the photocatalytic treatment to achieve almost complete detoxification of the irradiated solution. (C) 2014 Elsevier B.V. All rights reserved.