Landfill leachate is regarded as a great threat to environment and its remediation is very complicated task due to its recalcitrant nature. Consequently, strategies based on integrated physic-chemical-biological techniques must be evaluated. This work propounds a combined treatment line for a particular landfill leachate, consisting of a preliminary physic-chemical stage followed by an Advanced Oxidation Processes (AOPs) by means of solar photo-Fenton and a final conventional biotreatment. Additionally, an economic evaluation of the proposed treatment line is presented. The results obtained for a landfill leachate sample containing a high organic load (landfill leachate of around 40 g/L as COD and 15 g/L as DOC) revealed that this technologies combination is effective reducing recalcitrant organic content after the conditioning step (17% DOC removal), requiring then a solar photo-Fenton (Fe 1 mM) treatment time of 11 h that generates a non-toxic and biodegradable effluent mineralization percentage needed to achieve an appropriate biodegradability was 27%, requiring a consumption of 22 g H2O2/L. Total costs have been assessed in around 40 (sic)/m(3). (C) 2014 Elsevier B.V. All rights reserved.