The aim of the present work is to apply the liquid-liquid interfacial crystallization using a piezoelectric inkjet nozzle to the sol-gel processing. The instillation process was compared with the batch process to elucidate the effectiveness of the inkjet technique on the liquid-liquid interfacial sol-gel processing. The effect of frequency and water concentration in titanium tetraisopoxide (TTIP) solution on titania particle properties was investigated for sol-gel processing with a piezoelectric inkjet nozzle. Titania particles produced by each process were calcined at 500 degrees C. The crystal structure, morphology, pore size distribution and specific surface area of titania particles were evaluated by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), nitrogen physisorption measurement. The photocatalytic activity of titania particles was evaluated by the photodegradation of methylene blue solution under UVC light irradiation. Monodispersed titania particles could be produced by instillation sol-gel processing of hexane using a piezoelectric inkjet nozzle. Titania particles prepared at 1500 Hz were spherical while titania particles prepared at 1000 Hz and 3000 Hz were non-spherical. The number of particulate fracture increased with water concentration in TTIP solution. The inkjet nozzle-mediated instillation processing was found to be a promising way to create porous titania particles with a high photocatalytic activity. (C) 2014 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.