This review highlights the use of atropisomeric (axially chiral) chromophores for stereospecific photoreactions. The presence of axial clairality in the substrate imparts excellent stereo (enantio- and diastereo-) control affording high selectivities in point chiral photoproducts. 6 pi-Photocyclization and [2 + 2]-photocycloaddition are detailed as exemplars to highlight the richness and diversity of atropisomers undergoing photochemical transformations.