The adsorption of mesoporous Fe3O4-SiO2-TiO2 (MFST), which can be separated easily from solution by a magnet, for the removal of methyl orange (MO) was investigated. The nitrogen adsorption-desorption measurement shows successful synthesis of MFST with an average pore size of 3.8 nm and a large specific surface area of 55 m(2).g(-1). About 95% adsorption percentage of MO is achieved with an initial concentration of 10 mg.L-1 in the dark and the MFST exhibits superior adsorption ability under acid conditions. The adsorption data fit well with the pseudo-second order model for adsorption. After 4 cycles, the adsorption rate for MO remains 74% in the dark and the MFST can be recovered in a magnetic field with a recovery of about 80 % (by mass). It demonstrates that the samples have significant value on applications of wastewater treatment. (C) 2014 The Chemical Industry and Engineering Society of China, and Chemical Industry Press. All rights reserved.