This paper reports on a full evaporation headspace gas chromatography (FE HS-GC) technique for rapid determination of the ethyl laurate content in supercritical ethanolcarbon dioxide mixtures. The data show that, at an equilibration temperature of 150 degrees C, with a small volume (up to 75 mu L) of sample, the full evaporation of ethyl laurate can be achieved in 3 min. The method had a relative standard deviation of less than 5.5% in replicate measurements; the limit of quantification (LOQ) was 26.0 mu g; and the recovery ranged from 96 to 105%. The method is simple and rapid. It is quite suitable for use in the determination of ethyl laurate or similar compounds in an ethanolcarbon-dioxide-based supercritical reaction system.