Using of mineral particles in coatings and insulators to reduce thermal dissipation through the walls of buildings is one of the great importance and is of especial significance. It is recently attached to paints containing mineral micro particles as thermal insulation in order to prevent loss of energy in various industries and buildings. In the present work, in order to investigate the flow field, temperature distribution and heat transfer in a room with a radiation cooling panel, a three-dimensional enclosure is simulated under various boundary conditions. The effect of using a coating containing mineral micro particles in lieu of regular acrylic paint, on temperature distribution and heat transfer is studied in various states and under different climatic conditions and the results are compared. It was observed that coatings containing mineral micro particles act as thermal insulation and reduce energy consumption by about 20%. Besides, using of cooling panels to provide the cooling load, along with using of mineral micro particles in external walls, gives better results for hot and dry and hot and humid weather conditions. (C) 2014 Elsevier B.V. All rights reserved.