This work focuses on the scheduling of an in-line diesel blending and distribution subsystem of an oil refinery. The formulation is based on a hybrid time representation in which time points are equally distributed along the time horizon, within which time slots of variable length are postulated. The hybrid time representation takes advantage of the flexibility of the continuous time representation and enables handling of intermediate due dates with the use of fixed time points. Time variables are defined in terms of resources instead of transfer operations leading to a smaller size formulation. Results from a real-world case are used to validate the proposed formulation that takes into consideration capacities and operating rules while minimizing costs. Results of the multiperiod scheduling are also compared to a day-ahead production planning policy. Computational efficiency is achieved after adding valid inequalities and symmetry breaking constraints.