Part 1 of this series of papers proposed an improved ternary diagram for designing a resource conservation network (RCN) with multiple properties with a direct reuse scheme. In this part of the series, an RCN with a regeneration scheme is synthesized via the improved ternary diagram approach. The first literature example presented in part 1 of this series of papers is revisited to illustrate the improved approach. In addition, a sour water system of an operating refinery is illustrated to show the feasibility and effectiveness of the improved approach.