An assessment of the heat and mass transfer wall boundary conditions used for subcooled boiling simulations with a CFD two-fluid model has been performed. This assessment was focused on the wall heat flux partitioning model using the state-of-the-art multidimensional Freon experimental data available in the literature. Various constitutive relations used to close the vapor generation rate at the heated wall were studied in order to obtain the best suited combination(s). The current study was restricted to vertical flows through pipe and annulus geometries. Two Freon data sets from the literature were considered: the first with R12 at about 2.6 MPa pressure and the second with R113 at 269 kPa pressure. In these data sets, the bubble diameter distribution measurements across the ducts were available. Bubble diameter estimation is the largest uncertainty in the boiling two-fluid model predictions and hence using the data with known bubble sizes allowed to focus on the assessment of other parameters to model vapor generation rate at the wall, in particular bubble nucleation site density and bubble departure frequency. From the parametric simulations with different combinations of the nucleation site density and frequency models, the discrepancy in obtaining a consistent frequency model for Freon became evident The state-of-the-art frequency model under consideration is a function of the wall temperature which is estimated using a well-known empirical nucleate boiling heat transfer coefficient correlation. The frequency model provided inaccurate predictions in cases where the nucleate boiling heat transfer coefficient was inadequate to predict the wall superheat. The frequency model is now improved by using a more recent nucleate boiling heat transfer coefficient correlation with wider applicability, i.e., Freon. The simulations were carried out using the CFD code CFX (version 12). The Freon data used here corresponds to fluid-vapor density ratios ranging from 6 to 76. This assessment validated a consistent site density-departure frequency correlation combination for subcooled boiling simulations which has not been used so far for CFD simulations and an extension of the applicability of the correlation combination to high pressure steam-water conditions due to the favorable scaling of Freon physical properties. (C) 2014 Elsevier Ltd. All rights reserved.