This paper investigates a mathematical simulation of the heat and mass transfer in the two different Maisotsenko Cycle (M-Cycle) heat and mass exchangers used for the indirect evaporative cooling in different air-conditioning systems. A two-dimensional heat and mass transfer model is developed to perform the thermal calculations of the indirect evaporative cooling process, thus quantifying the overall heat exchangers' performance. The mathematical model was validated against the experimental data. Numerical simulations reveal many unique features of the considered units, enabling an accurate prediction of their performance. Results of the model allow for comparison of the two types of heat exchangers in different applications for air conditioning systems in order to obtain optimal efficiency. (C) 2014 Elsevier Ltd. All rights reserved.