Catalytic performance of Ru/NixMg6-xAl2 800 800 mixed oxides, with x = 2, 4 and 6, x being the molar ratio, towards Methane Steam Reforming, was studied. NixMg6-xAl2 800 oxide, used as support, was prepared via hydrotalcite route. It was thermally stabilized at 800 degrees C, impregnated with 0.5 wt.% ruthenium using ruthenium (III) nitrosyl nitrate Ru(NO) (NO3)(3) precursor and then calcined again at 800 degrees C under an air flow. Ruthenium impregnation significantly enhanced the reactivity of the oxides in Methane Steam Reforming. In fact, it was found, that even with a low ruthenium content (0.5 wt.%), ruthenium oxide particles are formed but are well dispersed over the surface of the oxide NixMg6-xAl2 800. Ru/Ni6Al2 800 800 showed better catalytic performances, towards Methane Steam Reforming, than ruthenium impregnated on the two other supports. Indeed, nickel content is higher in Ni6Al2 800 than in the other studied supports and therefore the probability of Ni-Ru interaction should be greater and consequently catalytic performances could be improved. Copyright (C) 2014, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.