The synthesis and characterization of an efficient and reusable catalyst, SBA-15/CCPy/Pd(II) nanocatalyst by grafting of melamine bearing pyridine groups on SBA-15 and subsequent generation of Pd nanoparticles, are described. The catalyst has been characterized by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray (EDX), inductivity coupled plasma (ICP), nitrogen adsorption-desorption, and Fourier transform infrared (FTIR) spectroscopy. The catalyst is used in Suzuki cross-coupling reaction of various aryl halides, including less reactive chlorobenzene, and phenylboronic acid to give biaryls without any additive or ligand. These cross coupled products were produced in excellent yields under mild conditions at extremely low palladium loading (similar to 0.3 mol%) with significantly high turnover frequencies (TOFs). The heterogeneous catalyst can be readily recovered by simple filtration and reused 7 times without significant loss in its activity. (C) 2014 Elsevier B.V. All rights reserved.