For about 300 Solvents, we propose, a database of new solvent parameters describing emphically solute/solvent interactions: DI for dispersion and induction, ES, for electrostatic interactions between permanent multipoles, alpha(1) for solute Lewis, base/solvent Lewis acid interactions, and beta(1) for solute hydrogen bond donor/solvent hydrogen bond.acceptor interactiOns. The main advantage over preVioris parametrizations is the Osiness, of extension, of this database to newly designed solvents, since only three probes, the betaine dye 30, 4-fluorophenol, and 4-fluaroanisale.are required. Thee parameters can be 'entered into the linear salvation energy relatioriShip A = A(0) + di(DI) + eES + a alpha(1) + b beta(1) to predict a large-number Of 'varied physicochemical,propertio A and to rationalize the multiple intermolecular forces at the origin of solvent effects.