Tanshinone IIA (TS) and cryptotanshinone (CT) are phenolic compounds which show significant biological potential. This study deals with the optimization and kinetics of TS and CT extraction from the rhizome of Salvia miltiorrhiza Bunge in a stirred batch extraction. The influence of various extraction parameters on the extraction yield has been studied. The optimum extraction conditions are 85% ethanol, solid to solvent ratio of 1:20, 333.15 K of temperature, agitation speed of 300 rpm, 0.09 to 0.125 mm of powder size and extraction time 30 min. 2.72 mg and 1.78 mg per gram of the rhizome powder of Salvia miltiorrhiza Bunge for TS and CT are obtained in the optimum extraction conditions, respectively. The extraction kinetics behavior of TS and CT from the rhizome powder of Salvia miltiorrhiz Bunge reveals that the extraction of TS and CT follows the first order kinetics. The kinetic expression developed by Spiro and Siddique is used and the model is in good agreement with the experimental results. The activation energy for the extraction of TS and CT is found to be 16.05 kJ/mol and 18.82 kJ/mol, respectively.