This paper investigates the problem of robust observer-based stabilization for a class of one-sided nonlinear discrete-time systems subjected to unknown inputs. We propose a simple simultaneous state and input estimator. A nonlinear controller is then proposed to compensate for the effects of unknown inputs and to ensure asymptotic stability in a closed loop. Several mathematical artifacts are used to deduce stability conditions expressed in terms of linear matrix inequalities. To show high performances of the proposed technique, a relevant example is provided with comparisons to recent results.