Densities, rho, ultrasonic speeds, u, and viscosities, g of solutions of glycine/l-alanine/l-valine/l-isoleucine in water and aqueous-streptomycin sulfate {1% (0.0069 mol.kg(-1)) and 2% (0.0137 mol.kg(-1)) streptomycin sulfate in water} mixed solvents were measured at T (293.15, 298.15, 303.15, 308.15, 313.15, and 318.15) K and atmospheric pressure. From these experimental results, the apparent molar volume, V-phi, limiting apparent molar volume, V-phi(boolean AND) /and the slope, S-v, apparent molar compressibility, K-s,(phi), limiting apparent molar compressibility, K-s,phi(degrees) and the slope, S-k, transfer volume, V-phi,V- (degrees)(tr), transfer compressibility, K-s,phi,tr(degrees), limiting apparent molar expansivity, E-phi(degrees), Falkenhagen Coefficient, A, Jones-Dole coefficient, B, hydration number, n(H), and temperature derivative of B-coefficient, dB/dT were calculated. Also, the activation parameters such as the free energies of activation of viscous flow per mole of solvent, Lambda mu(degrees#)(1) and per mole of solute, Delta mu(degrees#)(2), were calculated and discussed in terms of transition state theory. The results are interpreted in terms of (solute + solvent) and (solute + solute) interactions in these systems. It has been observed that all these amino acids act as structure-breaker in aqueous-streptomycin sulfate solvents. In addition to this, V-phi(degrees), K-S,phi(degrees), B and Delta mu(degrees#)(2) have been split into group contributions of the amino acids using linear correlation with number of carbon atoms in the alkyl chain of the amino acids. (C) 2015 Elsevier Ltd. All rights reserved.