Past-accident analysis shows that most dangerous incidents are related to process operations. Often these operations are carried out under high pressures and/or high temperatures. The consequences, therefore, are significant. A scientific analysis of past accidents which led to vapour cloud explosion has been performed. The analysis has provided vital information for most probable accident scenarios for a new situation. Factors such as chemical characteristics, its release mode, time etc. show trends and relationships for the occurrence of vapour cloud explosions.