Vapor phase synthesis of annelated pyridines from cyclic ketones, aldehydes and ammonia was carried out over various zeolite molecular sieves like H beta, HZSM-5 (240), HZSM-5 (40), HY, HX, HMCM-41 and Mordenite. The preliminary screening of catalyst clearly shows that H beta catalyst was found to be more active for the vapor phase synthesis of annelated pyridines. H beta was further modified with transition metals like Fe, Cu, Pb, Mo, Zn, Ni, Co, Ce, W and Sn to get higher yields.