This article witnesses the magneto-hydrodynamic flow of viscous fluid in a channel with non-parallel walls. Heat and mass transfer effects are taken into account. Thermo-diffusion and diffusion-thermo effects are considered to analyze the behavior of temperature and concentration profiles. Influences of first order chemical reaction are also studied. Problem is formulated for velocity, temperature and concentration fields using similarity transforms. Analytical and numerical solutions are obtained using well known Homotopy Analysis Method and Adomian's Decomposition Method (ADM). A numerical solution using Runge-Kutta method is also presented for the sake of comparison. Comprehensive graphical analysis coupled with discussions is carried out to study the effects of different emerging parameters on temperature and concentration profiles. Graphical aid is also used to present the variations in Nusselt and Sherwood numbers. A comparison of the solutions obtained in this article to the one available in open literature is also the part of study. (C) 2015 Elsevier Ltd. All rights reserved.