Defined tetrahedral agglomerates have been produced from macroscopic spherical primary particles and a liquid binder by using a lab-scale pelletizing pan. These defined tetrahedral agglomerates consist of four spherical primary particles, three particles forming the base area on which the fourth particle is arranged centrally. The compression and breakage behavior has been experimentally studied by compression tests. The influence of particle size and binder concentration has been investigated. Moreover, a first approach regarding the theoretical description of the contact deformation of tetrahedral agglomerates has been derived.