This paper presents an experimental investigation on two-phase driven ejector performance characteristics in a novel ejector enhanced refrigeration system (NERC). An experimental setup using refrigerant R600a is designed and built based on the NERC system. In the experimental setup, the ejector uses two-phase refrigerant coming from the high-temperature evaporator as the primary fluid. The experiments are carried out to examine the influences of the main operational and geometric parameters, including the primary fluid pressure, the secondary fluid pressure, the NXP and the nozzle throat diameter. The results show that the entrainment ratio, the pressure lift ratio and the overall ejector efficiency of the two-phase driven ejector are strongly affected by those parameters. Additionally, the effect of the quality of the two-phase primary fluid is also experimentally investigated. The meaningful results obtained here may serve as good guidelines for further improving the two-phase driven ejector performance and providing promising use of the two-phase driven ejector in the ejector-expansion technology. (C) 2016 Elsevier Ltd. All rights reserved.