Grape seed oil is recognized for its high quality bioactive compounds, however, these are sensitive to increased temperatures during manufacture. Technical and economical potential of the pretreatment in combination with the mixture of hydrolyzing enzymes have been analyzed. It was confirmed that the shockwave pretreatment significantly enhances the subsequent enzymatic hydrolysis, which subsequently better liberates the vacuoles rich in oil (without exceeding the temperature limitation). The assessment of oil yields achieved together with the holistic cost analysis indicates that this technology has significant technical potential. Admittedly, it still faces difficulties linked with increased cost of production.